| Description | DNA contains the genetic code. Even though the DNA code in all our cells (in brain cells, skin cells, blood cells, etc) is exactly the same, these cells function very differently. Skin is very different from blood and brain! How is this possible? It is possible because there is an extra layer of code, beyond the genetic code, that regulates these different functions. This epigenetic code is organized in space and time (4D). The project aims to figure out what this code is and how this code is embedded in chromatin. This is a computational/simulation project. |
|---|---|
| Number of students | 2 |
| Year of study | Students in their 1st year (Semester 1), Students in their 2nd year (Semester 3), Students in their 3rd year (Semester 5), Students in their 4th/5th year (Semester 7/9) |
| CPI | 8 and above |
| Prerequisites | Knowledge of programming and readiness to work on simulation |
| Duration | 1 year |
| Learning outcome | A research publication |
| Weekly time commitment | Five hours a week (one hour every working day) |
| General expectations | The student needs to be passionate and be ready to do research for a duration of one year at least. The student must spend one hour time in my lab every working day doing research (any time during the day). |
| Assignment | https://www.bio.iitb.ac.in/~ranjith/ |
| Instructions for assignment | Go through the material linked above before the interview |
| Description | We are working on developing a laser speckle bases imaging system to image blood flow in animal and human brains. The work is translation in nature and hence in need of a prototype development for possible commercialization. We need students interested in developing software algorithms for interfacing the imaging hardware system (lasers, camera, etc) with a GUI. We also do theoretical/ computational work in the laser speckle imaging domain. Students are free to choose the problems that they fit well. |
|---|---|
| Number of students | 2 |
| Year of study | Students in their 2nd year (Semester 3), Students in their 3rd year (Semester 5) |
| CPI | None |
| Prerequisites | None |
| Duration | 1-2 years |
| Learning outcome | Developing hardware and software, translation, and prototype development of optical imaging systems |
| Weekly time commitment | 3-4 hours |
| General expectations | None |
| Assignment | https://opg.optica.org/boe/fulltext.cfm?uri=boe-11-11-6699&id=441990 https://opg.optica.org/boe/fulltext.cfm?uri=boe-13-11-6081&id=512855 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774864/ |
| Instructions for assignment | Read all the above 3 papers and make a half-page summary for each one. |
| Description | Impairment of gait (walking) is a major problem in many neurodegenerative disorders such as Parkinson's disease and Huntington's disease, resulting in functional dependence and poor quality of life. Rehabilitation involving gait training is one of the primary approaches to treatment in such cases. Whilst there are several common features underlying impaired gait across different diseases, disease-specific gait characteristics often remain unmasked. For better differential diagnosis, prognosis, as well as for optimal delivery of rehabilitation, it is important to understand disease-specific determinants of impaired/pathological gait. The project will focus on developing statistical models to understand the unique determinants of impaired gait across common neurodegenerative disorders. |
|---|---|
| Number of students | 1 |
| Year of study | Students in their 2nd year (Semester 3), Students in their 3rd year (Semester 5), Students in their 4th/5th year (Semester 7/9) |
| CPI | 8.5 and above |
| Prerequisites | Strong background in mathematics is essential. Some coursework/knowledge in statistics would be desirable. |
| Duration | Minimum: one full semester. The project may continue beyond a semester if interest and commitment persist. |
| Learning outcome | 1) Gaining first-hand experience of application of mathematical and engineering analytical knowledge in solving biomedical/health related problems. 2) Exposure to advanced data analysis and statistical modelling. 3) Understanding of human gait control from a neuroscience and biomechanics perspective and clinical problems therein. |
| Weekly time commitment | 5 to 10 hours per week |
| General expectations | - |
| Assignment |
1) Textbook: Gait Analysis: Normal and Pathological Function
by Jacquelin Perry (Chapters 1-3) https://www.bio.iitb.ac.in/~ranjith/ 2)Review Paper 1 Review Paper 2 Review Paper 3 |
| Instructions for assignment | Students are expected to read at least 1 review paper (reading all 3 would be great; textbook chapters are to help gain basic understanding of terminology and concepts), gain a preliminary understanding of the topic(s) discussed in these papers, and briefly summarize their takeaways and how this background relates to the project topic. |
Dive deep in the realm of Academic and Industry related research projects
Created with ❤️ by UGAC Web Team, 2023-2024